During this time, her steadfast commitment to the liberation of South Africa saw her elected to the position of Vice Chairperson of the ANC Regional Political Committee in Great Britain between 1978 and 1988, and she later became its Chairperson from 1988 – 1989.
Between 1980 and 1985, Dr. Dlamini Zuma served as Paediatric Medical Officer at the Mbabane Government Hospital in Swaziland. During this period, she completed a postgraduate Diploma in Tropical Child Health at the School of Tropical Medicine, University of Liverpool in 1986. She did an attachment at the Wittington Hospital’s Paediatric section between 1987 and 1988. During this time, she founded and directed the Health Refugee Trust (HEART) of the Health and Development Organisation in England. She was deployed to the ANC’s Health Department in Lusaka, Zambia between 1989 and 1990, where she was part of the health leadership not only in healthcare of the community in exile, but also in the drafting of post-apartheid health policies. She also participated in the Women’s section of the ANC.